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i have found that the side effects of serouel (drowsiness restless feet etc...) last between 6 to 9 hours. however the antipsyhcotic effect seems to last right through the next day if you are taking your dose at night with your main meal side effects seem to hang on a little longer for some reason and may have trouble waking up next morning so i have tended to take my seroquel about an hour before my main meal and sleep right through the side effedcts.
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