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What happens when a stimulus activates a receptor?
The activation of a second messenger inside the receiving cell, the triggering of enzyme activity in the cell, and the change of permeability of the cell.
Why g protein are coupled receptors?
The receptor it self is a trans-membrane protein and doesn't act as an ion channel further more the G-protein involves several functions by its different subunits (G-alph: activation of PLC and adenylcyclase. and G-beta,gamma: activation of potassium channel) and the receptor is coupled with more than one G-protein which lead to amplification of the signal. So G-protein could be possibly evolved to do several functions and amplify them by one receptor
When protein membrane receptors are activated what usually happens?
When protein membrane receptors are activated, they usually undergo a conformational change, which triggers a downstream signaling cascade. This cascade can involve the activation of intracellular proteins or the production of second messengers, leading to a variety of cellular responses such as gene transcription, enzyme activation, or changes in cellular metabolism. Ultimately, the activation of protein membrane receptors initiates a cellular response to the signaling molecule that bound to the receptor.
What is receptor desensitisation?
Receptors generate a cellular response upon binding their specific ligand. This response can vary in magnitude. Desensitisation is a phenomenon in which activation of a receptor can reduce the magnitude of the response if it is subsequently activated again. Usually the longer a receptor is activated for the greater the desensitisation will be. There are 3 general mechanisms as to how desensitisation occurs. The first is uncoupling of the receptor from proteins which generate the cellular response. The second is internalising receptors so that they cannot be activated. The third is reducing production of receptors so less are available. In general mechanism 1 is short term, 2 is mid-term and 3 is long term.
What does an enzyme do to activation energy?
Enzymes generally lower the activation energy of a reaction, making them easier to take place.
Activation of which kind of receptor causes heart rate to increase?
beta-one receptor
The activation of receptor tyrosine kinases is characterized by what?
Dimerization and phosphorylation
The activation of receptor tyrosine kinases is characterized by?
dimerization and phosphorylation.
Is CD4 an adhesion molecule?
The glycoprotein CD4 is a co-receptor. A co-receptor is "a cell surface receptor, which, when bound to its respective ligand, modulates antigen receptor binding or affects cellular activation after antigen-receptor interactions." (MediLexicon)
How does serotonin receptor down-regulation have an antidepressant effect if it results in a decrease in post-synaptic neuron activation?
The serotonin receptor down-regulation has an antidepressant effect if it results in a decrease in post-synaptic neuron activation by activation of the 5-HT receptors within the rostral ventrolateral medulla.
Which of the choices below is not a factor required for target cell activation by hormone receptor interaction?
A type of hormone
How goserelin works on downregulation of gnrh?
Goserelin is an GnRH receptor agonist and bings stronger than GnRH. Due to the constant activation of the GnRH receptor (Goserelin binds really strong; Superagonist) the cell internalizes the receptor -> Downregulation.
How long does it take to get an activation code from wattpad?
When Wattpad sends an activation email, it is usually right away. If you do not get the activation email within one hour, you should request for them to send you another one.
How long does it take to receive an activation code in Maplestory?
It should be less than a hour
What is receptor internalisation?
Receptor internalization is the process by which cell surface expressed receptors are monoubiquitinated following ligand-induced activation, and subsequently taken up into the endocytic vesicles to the lysosome. The receptor will either be degraded or brought back to cell membrane were it is again able to interact with its ligands. Receptor internalization serves as a mechanism to downregulate receptor signaling upon agonistic ligand stimulation.
How long do you have to wait for the runes of magic activation email?
it can normally take up to 3 months
How long does it take for the activation message in Minecraft to come to your email?
It took mine about 1 week
