does ti have a nephew named Michael
Frank Lampard has 2 Nieces and 1 Nephew, Millie, Mia and Stanley - Mia & Stanley are brother & Sister
well his daughter is Star and he's nieces are Baby Doll and Beauty....
Act
he izway 2 sexii 2 have aids!!!!
Not necessarily. Simply put, a low TI indicates that the dose that causes a beneficial effect is "close" to the dose that causes unacceptable toxicity or lethality. A drug with a large or wide TI means that the dose that causes the beneficial effect is far lower than the dose that causes toxicity or lethality. If a drug has a TI of 2, then the drug dose that causes toxicity is twice that which causes the benefit. So a mistake of taking 2 pills instead of 1 can be disastrous. If a drug has a therapeutic index of 13, then the dose expected to cause toxicity is 13x that which causes the toxic effects, and is pretty safe. To compare effectiveness of a drug, you have to compare drug efficacy and TI. For a large TI drug, sometimes you just need to increase the dose. In the example above where TI=13, you could increase the dose 6 0r 7 times and you may not see an increase in toxic effects.
Aunt Jane's Nieces Out West has 316 pages.
Aunt Jane's Nieces at Work has 298 pages.
Aunt Jane's Nieces on the Ranch has 276 pages.
Aunt Jane's Nieces on Vacation has 305 pages.
Aunt Jane's Nieces at Millville has 306 pages.
Aunt Jane's Nieces in Society has 264 pages.
Aunt Jane's Nieces Abroad has 347 pages.