too high or too low pH denatures the enzymes. you will get a small reaction with a base or acid. neutral pH level maximizes reactions
If there is too much base or too much acid, then it can change the course of the chemical reaction.
at a ph of 13
The stomach secretes protease enzymes that work best at a pH of around 2.
temperture.
Following are the factors affectingenzymes:SalinityTemperatureInhibitorsAllosteric factorspH levelSubstate concentrationCatalystEnzyme concentration
enzymes found in human bodies require different pH . like pepsin requires 1 or 2 to work, while trypsin requires 8. but overall the pH ranges from 6-8 for optimum efficiency
Temperature, pH, substrate concentration
All enxymes work at an optimum pH. Changes in pH levels could change the rate at which the enzymes work by denaturing them.
enzymes require specific temperature and pH in order to work properly. Otherwise, the temperature or pH change their conformation or disable their ability to bind the substrate because the required electrostatic interactions might not happen under different pH.
Most enzymes only work in a certain pH range; pH is not dependent on the presence of enzymes, however.
tempeture,ph, solute concentration and salt content
Substrate concentration will affect enzymes because substrates are specific to enzymes. The pH will affect enzymes because certain enzymes will work better in certain pH levels.
Enzymes are very pH-sensitive. Any change in pH results in denaturing of proteins.
Most enzymes work best at a certain pH, however there are some enzymes that can operate over a broad pH range.
it can change the shape of enzymes & active site so the enzyme is unable to work
The activity of the enzymes depends on the specific pH needed.
at a ph of 13
Enzymes are designed to work at their optimum pH. This is the level at which they will work the fastest. If the pH around an enzyme becomes too high or too low, the protein structure of the enzyme will be denatured. This is a irreversible effect, and the enzyme cannot carry out its function, and is thus useless (you can think of it as dead)