Asked in Conditions and DiseasesExerciseVitamins and SupplementsHow To
Conditions and Diseases
Vitamins and Supplements
How to prevent lactic acidosis?
Asked in Chemistry, pH Levels
What does a buildup of lactic acid do to the pH of muscle cells?
What causes metabolic acidosis?
There are three major forms of metabolic acidosis that occur in the human body. The first type is diabetic acidosis where ketones build up in the blood. The second type is lactic acidosis, when the body produces too much lactic acid, and the third type of acidosis is hyperchloremic acidosis which occurs when there is a loss of sodium bicarbonates.
Asked in Respiratory System
Can respiratory acidosis and metabolic acidosis occur at the same time?
Yes in cases like copd and renal failure ...... opioid poisoning with sepsis. The cause of respiratory acidosis is the excess C02 secondary to the rate of respiration (breathing rate low or circulatory problems). Lactic acidosis is due to the incomplete metabolism of glucose. Other forms of metabolic acidosis are symptomatic of kidney failure.
Asked in Biochemistry, Respiratory System
Distinguish between acidosis and alkalosis resulting from respiratory and metabolic factors?
1)Respiratory acidosis results from carbon dioxide retention; respiratory alkalosis occurs when carbon dioxide is eliminated faster than it is produced. 2)Metabolic acidosis occurs when fixed acids (lactic acid, ketone bodies, and others) accumulate in the blood or when bicarbonate is lost from the body; metabolic alkalosis occurs when bicarbonate levels are excessive. Distinguishing factors between respiratory and metabolic acidosis is that in respiratory acidosis, the CO2 is increased while the bicarbonate is either normal (uncompensated) or increased (compensated). Compensation occurs if respiratory acidosis is present, and a chronic phase is entered with partial buffering of the acidosis through renal bicarbonate retention.
Asked in Biology, Medical Terminology, Cardiologists
What is the medical term meaning Blood pH of 7.3?
Definition Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids). Causes, incidence, and risk factors The kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory acidosis or metabolic acidosis. Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused when the body is unable to remove enough carbon dioxide through breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include: Chest deformities, such as kyphosis Chest injuries Chest muscle weakness Chronic lung disease Overuse of sedative drugs Metabolic acidosis develops when too much acid is produced or the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes. Hyperchloremic acidosis is caused by the loss of too much sodium bicarbonate from the body, which can happen with severe diarrhea. Lactic acidosis is a buildup of lactic acid. This can be caused by: Alcohol Cancer Exercising vigorously for a very long time Liver failure Low blood sugar (hypoglycemia) Medications such as salicylates MELAS (a rare genetic disorder that affects energy production) Prolonged lack of oxygen from shock, heart failure, or severe anemia Seizures Other causes of metabolic acidosis include: Kidney disease (distal renal tubular acidosis and proximal renal tubular acidosis) Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanol Severe dehydration Symptoms See: Metabolic acidosis Respiratory acidosis Signs and tests An arterial blood gas analysis or serum electrolytes test, such as a basic metabolic panel, will confirm that acidosis is present and indicate whether it is metabolic acidosis or respiratory acidosis. Other tests may be needed to determine the cause of the acidosis. Treatment Treatment depends on the cause. Expectations (prognosis) Acidosis can be dangerous if untreated. Many cases respond well to treatment. Complications Complications depend on the specific type of acidosis. Calling your health care provider Although there are several types of acidosis, all will cause symptoms that require treatment by your health care provider. Prevention Prevention depends on the cause of the acidosis. Normally, people with healthy kidneys and lungs do not experience significant acidosis. References Seifter JL. Acid-base disorders. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 120. Reviewed By Review Date: 11/16/2011 David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Definition Metabolic acidosis is a condition in which there is too much acid in the body fluids. Alternative Names Acidosis - metabolic Causes, incidence, and risk factors Metabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances known as ketone bodies, which are acidic, build up during uncontrolled type 1 diabetes Hyperchloremic acidosis results from excessive loss of sodium bicarbonate from the body, as can happen with severe diarrhea Lactic acidosis is a buildup of lactic acid. It can be caused by: Alcohol Cancer Exercising for a very long time Liver failure Low blood sugar (hypoglycemia) Medications such as salicylates Prolonged lack of oxygen from shock, heart failure, or severe anemia Seizures Other causes of metabolic acidosis include: Kidney disease (distal tubular acidosis and proximal renal tubular acidosis) Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanol Severe dehydration Symptoms Most symptoms are caused by the underlying disease or condition that is causing the metabolic acidosis. Metabolic acidosis itself usually causes rapid breathing. Confusion or lethargy may also occur. Severe metabolic acidosis can lead to shock or death. In some situations, metabolic acidosis can be a mild, chronic (ongoing) condition. Signs and tests Arterial blood gas Serum electrolytes Urine pH Arterial blood gas analysis or a serum electrolytes test (such as a basic metabolic panel) will confirm acidosis is present and determine whether it is respiratory acidosis or metabolic acidosis. Other test may be needed to determine the cause of the acidosis. Treatment Treatment is aimed at the underlying condition. In certain circumstances, sodium bicarbonate (baking soda) may be given to improve the acidity of the blood. Expectations (prognosis) What can be expected will depend on the underlying disease causing the metabolic acidosis. Complications When very severe, metabolic acidosis can lead to shock or death. Calling your health care provider Seek medical treatment if you develop symptoms of any disease that can cause metabolic acidosis. Prevention Keeping type 1 diabetes under control may help prevent diabetic ketoacidosis, one type of metabolic acidosis. References Seifter JL. Acid-base disorders.In: Goldman L, Schafer AI, eds.Cecil Medicine. 24th ed.Philadelphia,PA: Saunders Elsevier; 2011:chap 120. Reviewed By Review Date: 11/17/2011 David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Difference in respiratory acidosis and alkalosis and metabloic acidosis and alkalosis?
Asked in Muscle Pain, Cell Biology (cytology)
How would athletes be affected if the process of lactid acid fermentation did not take place?
Lactic acid is produced during normal activity. Staying hydrated and keeping a balance between electrolytes keeps lactic acid from building up in muscles. However, strenuous activities can dehydrate the body, causing shifts in electrolytes. This can result in lactic acidosis which builds up in the muscles. At first, the person feels weak. If they rehydrate, they can stop the negative effects. However, if they do not rehydrate, lactic acidosis can progress. Respirations increase to try to lower the body's acidic level. However, respirations by itself cannot correct the condition without replacing fluids and electrolytes. Without this replacement, the muscles begin to spasm. The stomach can clench and cause pain and nausea. Leg muscles ache; weakness progresses. If the person cannot drink enough, they will need fluid replacement by IV. Athletes must stay hydrated, not only with plain water but with fluids containing electrolytes, like Gatorade, or they risk going into lactic acidosis.
Asked in Health, Conditions and Diseases, Diabetes
What classification of acidosis is diabetic ketoacidosis?
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Asked in Exercise
How can an athlete prevent a build up of lactic acid?
Asked in Chemistry
Definition Lactic acidosis is when lactic acid builds ups in the bloodstream faster than it can be removed. Lactic acid is produced when oxygen levels in the body drop. Causes, incidence, and risk factors The most common cause of lactic acidosis is intense exercise. However, it can also be caused by certain diseases, such as: AIDS Cancer Kidney failure Respiratory failure Sepsis Metformin, a common medicine used to treat diabetes, can also cause lactic acidosis. People taking this medicine should have their electrolyte levels checked 1 - 2 weeks after starting it. Symptoms Nausea Weakness Signs and tests Blood tests to check electrolyte levels Treatment The main treatment for lactic acidosis is to correct the medical problem that causes the condition. References Oh MS. Evaluation of renal function, water, electrolytes and acid-base balance. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management of Laboratory Methods. 21st ed. Philadelphia, Pa: Saunders Elsevier; 2006: chap 14. Collings JL. Acid-base disorders. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa:Mosby Elsevier;2009:chap 122. Reviewed By Review Date: 10/28/2010 Linda Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.