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I usually don't. As long as you throw out the moldy pieces, it's usually okay to eat the rest. (Or at least I've never gotten sick from doing that).

Another opinion . . .That depends what you want to do. Frequently, a piece of mold in one area of the loaf could mean that mold is growing elsewhere - you just can 't see it yet. I have had a whole loaf taste moldy, but located the mold on the last slices.
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Q: If one piece of bread has mold on it should you throw out the whole loaf?
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