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Answered 2008-12-16 18:17:53

You need to be sure you actually have two physically separate hard drives, and not just two partitions. If you do have 2 drives, then the second drive shouldn't be affected. However, I can't stress enough to BACK UP YOUR DATA before you do anything that could risk data loss. Formatting a physical drive will not change another physical drive directly, but the support files (dlls,libraries) that get loaded into the OS on drive A are gone and a lot of programs (even if the executables aren't deleted) will not work without a complete reload into the new OS.

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