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Is Requip a member of the family of benzodiazepenes The formula for diazepam and Requip are very similar during a recent drug screen while taking only Requip the test results had benzodiazepenes in it?


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2007-06-27 18:19:45
2007-06-27 18:19:45

No, diazepam is a benzodiazepine whereas Requip is an anti-Parkinson's drug. Requip works primarily on dopamine receptors in the central nervous system. Diazepam works on benzodiazepine receptors on GABA neurons. It is thought that Requip may have negligible activity at other GABA sites, but this is not its main mechanism of action. In terms of toxicity screen, I have not found data stating that Requip will give a false positive for benzos. High concentrations of fenoprofen, flurbiprofen, indomethacin, ketoprofen, and tolmetin (these are NSAIDS) may give a false-positive result by a TDx assay. Sertraline (Zoloft) may cause a false-positive urinary benzodiazepine assay using the original cloned enzyme donor immunoassay system

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