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Is a group of hereditary bleeding disorders in which a blood clotting factor is missing?
Wiki User
∙ 11y ago
hemophillia
Wiki User
∙ 11y ago
Wiki User
∙ 11y agoHemophilia
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What is a group of hereditary bleeding disorders in which a blood-clotting factor is missing?
Contradicting
Does hemophilia a and b have the same effects?
For the most part, yes. Both disorders effect clotting, both typically lead to the same types of bleeding and both range from severe to mild. They differ in which protein molecule is missing, but the results are pretty similar. (If your car were missing a tire, there would be some differences that depend on which tire was missing, however the overall effect would be pretty similar regardless of which tire was gone.)
Why do Hemophiliacs have trouble clotting their blood after injury?
When a hemophiliac has a cut, the air will dry the blood into something of a temporary a scab, but the patient is missing coagulation factors. They do not have something called fibrin that causes an actual clotting to occur. This means a real scab is not formed, and any little touch can cause the cut to begin bleeding again.
When someone can't stop bleeding?
There are various causes of slow blood clotting. A rare, but fairly well known condition, is Hemophilia. A person with Hemophilia is called a Hemophiliac. Only about 400 babies with the condition are born each year in the US. Most of the disorders in the body's ability to form blood clots to stop bleeding involve an hereditary absence of a clotting factor in the blood.Clotting factors are proteins carried in the blood that help form blood clots. They form the clots working with platelets, cells that were formed in the bone marrow, that are also in the blood. The platelets stick together to stop up an injured blood vessel with a clot that is held together with the help of the clotting factor proteins. Hemophiliacs can be helped by injections or intravenous infusions to replace the missing clotting factors.
What protein is missing or defective in hemophilia?
The proteins in the blood known as clotting factors!
What treatments are for hemophilia?
Hemophilia is treated by replacing the missing clotting factors intravenously.
Deficiencies of what could cause abnormally slow blood clotting time?
Slow clotting time means that bleeding takes a longer time to stop. It could be caused by - platelet deficiency or, - insufficient/missing clotting factors - anticoagulant therapy Platelets (normally) are tiny disc-shaped fragments of a big cell (megakaryocyte). They form a temporary plug over the injury site. They also release certain chemicals which help with coagulation if the plug is not enough to stop the bleeding. The condition, in what the absolute platelet numbers are less than sufficient, is called Thrombocytopenia. That could be the result of either the - bone marrow does not make enough platelets (leukaemia, radiotherapy), or - the platelets are destructed faster than the bone marrow makes them (immune disorders, drug therapy). It also could the caused by - viral infections, - Disseminated intravascular coagulation disease - Vitamin B12/folic acid deficiency - menstruation. Clotting factors are chemicals made mostly by the liver and some by the platelets. The clotting factors are either twelve or thirteen in numbers, (depending on how number V, Proaccelerin, and number VI, Accerelin is included in the count), include four factors that the liver can only make if there is enough Vitamin K in the body. Therefore, Vitamin K deficiency could also be one reason. Certain bleeding disorders can interfere with clotting. They might be caused by: - liver or renal disease, and again, - Vitamin K deficiency, - autoimmune diseases (Acquired Haemophilia, Acquired von Willebrand disease) - Genetic disorders (where certain clotting factors are not made: Von Willebrand disease, Haemophilia A, and Haemophilia B, the Christmas disease) Anticoagulant therapy - Warfarin - Heparin - Aspirin also do prolong the clotting time.
What are some treatments for hemophilia?
Hemophilia is treated by replacing the missing clotting factors intravenously.
Bleeding disorders?
DefinitionBleeding disorders are a group of conditions in which there is a problem with the body's blood clotting process. These disorders can lead to heavy and prolonged bleeding after an injury. Bleeding can also begin on its own.See also:Acquired platelet function defectsCongenital platelet function defectsCongenital antithrombin III deficiencyCongenital protein C or S deficiencyDisseminated intravascular coagulation (DIC)Drug-induced immune thrombocytopeniaFactor II deficiencyFactor V deficiencyFactor VII deficiencyFactor X deficiencyFactor XIIdeficiencyHemophilia AHemophilia BIdiopathic thrombocytopenic purpura (ITP)Von Willebrand's disease (type I and type II)Alternative NamesCoagulopathyCauses, incidence, and risk factorsNormal blood clotting involves as many as 20 different plasma proteins, which are known as blood clotting or coagulation factors. These factors act together with other chemicals to form a substance called fibrin that stops bleeding.Problems can occur when certain coagulation factors are low or missing. Bleeding problems can range from mild to severe.Some bleeding disorders are present at birth and are passed through families (inherited). Others develop from:Illnesses such as vitamin K deficiency or severe liver diseaseTreatments such as the use of drugs to stop blood clots (anticoagulants) or the long-term use of antibioticsBleeding disorders can also result from having poorly working or too few of the blood cells that promote blood clotting (platelets). These disorders can also be either inherited or picked up (acquired). The side effects of certain drugs often lead to the acquired forms.SymptomsAbnormal menstrual bleedingBleeding into jointsExcessive bruisingHeavy bleedingNosebleedsWhich problems occur depends on the specific bleeding disorder.Signs and testsComplete blood count (CBC)Bleeding timePartial thromboplastin time (PTT)Platelet aggregation testProthrombin time (PT)TreatmentTreatment depends on the type of disorder. It may include:Factor replacementFresh frozen plasma transfusionPlatelet transfusionOther therapiesExpectations (prognosis)The outcome also depends on the disorder. Most primary bleeding disorders can be managed. Those due to diseases, such as DIC, depend on how well the disease is treated.ComplicationsBleeding in the brainSevere bleeding (usually from the gastrointestinal tract or injuries)Other complications can occur, depending on the disorder.Calling your health care providerCall your health care provider if you notice any unusual or severe bleeding.PreventionPrevention depends on the specific disorder.ReferencesKessler C. Hemorrhagic disorders: Coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 180.
You skipped a pill and am bleeding?
Missing a birth control pill can result in breakthrough bleeding. As the hormone level in your body drops, bleeding can occur.
How is heamophilia treated?
The main course of treatment for hemophilia is replacement therapy. Via IV drips, clotting factors and added to the low or missing clotting factors detected in the patients system.
How hemophilia affect the body?
Your blood. A hemophiliac is a person who is a "free bleeder", meaning if they get even a minor cut, they will bleed profusely. If they get just a little more than a small cut, they can actually bleed to death because their blood does not clot the way it should.
