Is any orally administered drug has bioavailability 100 percent?
Many factors can contribute to affect the bioavailability of the orally administered drugs. Briefly, these includes gastric emptying rate, intestinal transit time, hepatic first pass metabolism, and gastrointestinal and hepatic blood flow etc. apart from these factors, disease conditions, diet and dosage form also contribute in alteration of the bioavailability of the drugs. Read More
yes Read More
Basically no, due to two reasons: First, the drug is incompletely absorbed from the gastrointestinal tract, some of it exits the body unabsorbed along with the feces. Second, the absorbed amount of the drug undergoes first-pass metabolism; where the drug enters the hepatic portal system and is partly metabolized by the liver, thus, the amounts of drug reaching the systemic circulation unchanged is even less. Therefore, the bioavailability of orally administered drugs is always below… Read More
It gets into the blood which carries it to the brain. Read More
Bioavailability of a drug is the amount of the drug that is available for use by the body after it has been metabolised by the liver. Read More
How does chemical stability of the drugs in the gastrointestinal tact affect the bio-availability of the drugs?
Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, so we need chemically stable drug in order to increase the chance of drug absorbance and thus increased bioavailability. Read More
A non-parenteral drug is one that is administered orally or by inhalation. Examples would be swallowing a pill or using an inhaler. Parenteral drugs are administered by injection or via transdermal patch (applied directly to the skin). Read More
Bioavailability is the amount of drug which reaches the site of physiological activity after administration. Read More
In layman's terms, bio-availability applies to "how much of this drug, when administered orally, is actually absorbed?" I.e how much of the drug is "available" for the body to utilize? What makes it a more confusing concept is that bio-availablity of the same drug, at the same dosage, is not the same for every person. (Although you can at least hope they are similar, which enables drugs to have standardized dosages). One of the primary… Read More
biovability of intral nasal route Read More
Bioavailability measures the amount of a drug (medicinal) or other substance which enters the blood. This depends on two types of factors: 1) The physical and chemical properties of the drug. If a drug is insoluble (ie does not dissolve) in the stomach or intestine it is unlikely to be absorbed into the blood, so its bioavailability will be low. If it is soluble it is more likely to be absorbed so its bioavailability will… Read More
A drug with a half-life of 12 hours is administered by continuous intravenous infusion How long will it take for the drug to reach 90 percent of its final steady-state level and why?
40 hours :) Read More
It is not recommended that you consume grapefruit products while taking this drug. Grapefruit increases the bioavailability of the drug, which increases the changes of drug toxicity. Read More
Insulin should be administered!! Read More
They can still have different bioavailability (the amount of drug that is delivered to the site of action and the rate at whcih it is available). Pharmacetical equivalents do not have to have the same release mechanisms, and can therefore affect their bioavailability. Read More
Avoids first pass effect in the liver and there is high bioavailability of the drug in the body. "Some medications are best administered into the subcutaneous tissue by a needle. This route has the advantage of almost complete absorption, providing the patient's circulation is good; therefore an accurate measure of the amount of the drug absorption is possible. Medicines administered in this manner are not affected by gastric disturbances (although it should be remembered that… Read More
A drug that is administered orally and has a broad spectrum of antibiotic activity. For the source and more detailed information concerning this subject, click on the related links section (Answers.com) indicated below this answer box. Read More
Glucocorticoids can make a person susceptible to infection when they are administered for too long as a drug. Read More
Pharamceutical agents which used in formulation to enhance the absorptuion of drug (through gastro intestinal tract) and hence its concentration in blood are called bioavailability enhancers. Some of the exaples are Cremophor, Gattefossse, Labrafil, Labrasol etc. Read More
What is the medical term meaning extent to which a drug or other substance becomes available to the body?
Bioavailability Read More
Chemotherapy works by the patient being administered the drug, either orally or intravenously. The drug targets cancer cells by a number of ways, but all aim to reduce the tumour's ability to grow and replicate. There are often side effects from these drugs as healthy cells in the body can also be affected, but most often these include nausea and vomitting, and tiredness. Read More
metoclopramide(trade name perinorm) it is an anti emetic drug. it can be administered by orally/Intravenously/intramuscularly while giving direct IV,slow IV is usually followed to avoid B P fall, Drowsiness etc. Read More
Balsalazide Read More
Yes, depending on the drug test administered, hydrocodone can be detected. Read More
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties. Read More
Fluxetine Read More
Caverject is indeed a drug. It is used to treat erectile dysfunction. It's administered by injection into the penis. Read More
What effect does crushing Dexedrine sr spanules have on potency efficiency and bioavailability of the active drug?
Enteric-coated drugs (time released/ sustained release capsules) don't disintegrate in the stomach b/c they are protected by the stomach acid. This drug has to reach an alkaline (non-acidic) environment (which is the small intestine) in order to disintegrate and get into the blood stream. Enteric coated tablets can remain in the stomach for a long time b/c they are protected from the acidic environment. Crushing dexedrine SR (beaded) capsules would alter the place and time… Read More
Parenteral means out side the intesine. Parenteral drug means the drug which is administered out side of the body.. Read More
IM means Intramuscular route of drug administration, while IV means Intraveinal route of drug administration. IV route, takes the drug directly into the bloodstream resulting in 100% bioavailability instantly. Where as in IM route, drug is injected into muscle tissues, which holds the drug for a while and gradually releases into the bloodstream through the network bed of capillaries running across or surrounding the muscle tissue. In IM, the bioavailability may be slightly less than… Read More
An inert substance that may be administered instead of a drug to see if it produces any of the same effects as the drug is called a?
Placebo Read More
per OS (latin for 'through the mouth' = (drug administration) orally) Read More
The two major routes are orally, by mouth, and injection. Read More
The drug is intended to be given to the patient either in an intramuscular injection - or by intravenous infusion. Used orally - it can cause problems in patients that have impaired liver functionality. Read More
Buprenorphine (Brand name Subutex and Suboxone) is not administered orally due to very high first-pass metabolism. The first-pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation. Read More
anxiolytic drug Read More
his doctor, who administered the drug that killed him. Read More
The stability of a drug is the ability of the drug to maintain its chemical, physical, therapeutic and toxicological properties throughout its shelf life. Often times environmental and other unexplainable factors affect the stability of drugs by causing degradation of either the active ingredient of the drug product or the excipients, reducing the bioavailability of the drug or changing the physical appearance of the drug. Read More
Acid (LSD) is usually absorbed through the skin. It can also be taken orally. Read More
A systemic drug means when a drug taken and it reaches to Blood is called systemic circulation. there are many ways for systemic drug administration like Oral, I.V, I.M, S.C Read More
"Orally disintegrating" and "mouth dissolving" both mean the same and are just flash names given to orally dissolvable tablets by drug companies. Read More
The percent of drug abuse in middle school is 52%. Read More
Chelation therapy involves injecting a drug called EDTA and drug taken orally called DMSA, together with nutrients into the bloodstream. Read More
This has to do with the route of administration. Some drugs are taken orally, some are inhaled. A drug taken parenterally is injected. Read More
Do non smokers in the same room with the marijuana smokers test positive when a drug test is administered?
No. Read More
Molly is a drug that is either in powder or pill form. Therefore, it is either taken orally or is snorted through the nose. It is both a stimulant and psychedelic drug. Read More
Fludrocortisone is the most common drug administered to hypotension patients. Also, doctors recommend more salt, more water, and compression socks. Read More