Is it okay to take SamE 5htp and Wellbutrin XL together since Wellbutrin works primarily on dopamine and the others on seratonin?

Of course, I must insist that you speak with your doctor about this, however...

It is thought, but not completely proven, that Wellbutrin works primarily on dopamine and norepinephrine, while SamE and 5-HTP affect serotonin.

This would lead one to believe that this combination is safe, personally I have taken Wellbutrin and 5-HTP together with no side effects.

Yet again, ask your doctor before combining a prescription drug with any other drug, chemical or herb.