You need to consult you physician on that matter. Depending on any pre-existing health conditions you may already have, your physician would be the only person competant to answer that question because of his/her extensive knowledge of your medical history. But for all intensive purposes I would think so. Generally... Yes. However it's important that you take it with food and as stated above, the only way to answer this definitely is if I knew more about your medical history; for instance if you are elderly, have gastric problems, kidney problems or one of a hundred other things then this would need further consideration.
Prozac is an SSRI that is metabolized by the CYP2D6 enzyme, and Ibuprofen is an NSAID that is metabolized by CYP2C9. There is no interaction that I am aware of between these two medicines. Yes, it is safe to take Ibuprofen. But if you have any doubts or further questions, ask your pharmacist. They will be glad to help.
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