I don't know if its safe or not but I would also like to know. As I took vicodin yesterday for some dental pain and am not feeling all that great today. I am currently taking 20mg of Prozac a day.
I am taking the same thing(20mg of Prozac) along with 600mg of lithium daily, and also have dental pain with vicodin prescribed. I called my pharmasist and he says that it is fine to take them together but that the vicodin will make you more tired than normal. The not feeling good after taking some vicodin thing is what I call a vic hangover, it happens to me after every time I have taken more than say 4 the day before.