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Can splenda kill you

Updated: 10/6/2023
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14y ago

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Splenda is made from sucralose. Results from over 100 animal and clinical studies in the FDA approval process unanimously indicated a lack of risk associated with sucralose intake. However, some adverse effects were seen at doses that significantly exceeded the estimated daily intake (EDI), which is 1.1 mg/kg/day.

A Duke University study found evidence that doses of Splenda of between 100 and 1000 mg/kg, containing sucralose at 1.1 to 11 mg/kg reduced the amount of good bacteria in the intestines of rats by up to 50%, increased the pH level in the intestines, contributed to increases in body weight, and affected the levels of P-glycoprotein (P-gp). These effects have not been reported in humans. An expert panel, including scientists from Rutgers University, New York Medical College, Harvard School of Public Health, Columbia University, and Duke University reported in Regulatory Toxicology and Pharmacology that the Duke study was "not scientifically rigorous and is deficient in several critical areas that preclude reliable interpretation of the study results". Another report suggests sucralose was a possible trigger for some migraine patients. Another study, published in the Journal of Mutation Research, linked large doses of sucralose equivalent to 11,450 packets (136 g) per day in a person to DNA damage in mice.

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13y ago
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10y ago

Though the FDA approved the use of Splenda as a sweetener in foods and some claim it is the perfect sugar substitute, others claim it is unsafe and has more in common with pesicides than table sugar. Though it is considered "natural," the term natural has no meaning when used on food labels, so that is misleading. Splenda is the trade name for sucralose, a synthetic (man made) compound discovered in 1976 by scientists in Britain who were seeking a new pesticide formulation. While it is true that the Splenda molecule starts out as sucrose, three of its hydroxyl groups have been replaced by three chlorine atoms.

The truth is, the safety of Spenda (sucralose) is not yet known. More studies are needed to determine its safety, especially long-term safety.

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11y ago

No - it is the best thing that ever happened to me. My Diabetes, which was totally out of control with blood glucose levels consistently above 600, is now well-controlled, with the use of insulin and the substitution of Splenda for sugar. I have lost 160 pounds, also with the help of Splenda being substituted for sugar. In fact, I have found that I am using less and less Splenda as my desire for sugary foods and sweets has greatly diminished.

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8y ago

In my humble opinion, Stevia is safer to use than Splenda. This is because Stevia comes from a natural plant.

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Wiki User

14y ago

no

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