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Sulfanamide a inhibitor of a metabolic pathway?

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They can work via allosteric inhibition, where the final product in large amounts binds to a site (not the active site, but an allosteric site) which stops the enzymes involved in the early phases of the metabolic pathway. In other words, the final product can act as an inhibitor to stop the enzyme early in the metabolic pathway by deactivating it.

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Enzymes are catalysts in metabolic pathways.

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A metabolic pathway that involvs both anabolism and catabolism.

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If an enzyme is defective in a metabolic pathway, the pathway will come to a halt and no product will be produced. Imagine a person walking to the store and not able to cross the street (flooded?).

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The metabolic pathway will predominate after eating a balanced meal is oxidative glycolysis. The citric acid cycle is a continuous circle of 8 metabolic reactions.


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