The direction that a river flows is called the flow or the drainages. Water generally flows downhill or from a higher elevation to a lower one.
Flow direction of a river varies according to the topography of the land. Elevation and gravity forces a river to flow downhill no matter which direction "down" is.
It is mainly known as it's course.
River
The river follows a sinous path through the forest.
The nation gambia follows a river called the Gambia River.
It's meander.
Orbit
No, the St. Lawrence River is not man made. But the St. Lawrence Seaway that follows part of the river's path is.
The path is called an orbit.
The path that the moon follows around the Earth is called an orbit. The planets going around the sun is called revolution. The moon goes around the Earth in a month.
Ellipse.
Orbit
Its called an orbit.