The enzyme that attaches nucleotides together by forming phosphodiester bonds between sugar and phosphate molecules during DNA replication is known as what?

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November 12, 2010 5:50AM

DNA Polymerase III attaches nucleotides to the leading and lagging strand in 5' --> 3' direction.

If you are referring to the lagging strand, then DNA Ligase will attach the Okazaki fragments together and connect the Phosphdiester backbone of the newly synthesized strand.