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are located in the same areas of the hypothalamus.
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What has the author Peter Shier written?
Peter Shier has written: 'Characterization of the gene encoding the insulin receptor-related receptor, IRR : a putative receptor for a member of the insulin family'
Growth factor hormones such as insulin bind to which type of receptor?
tyrosine kinase receptor!!
What does the acronym INSR stand for?
INSR is the acronym for Insulin Receptor. The insulin receptor watches over the action of insulin. INSR also stands for Insert, Input Shift Register and Integrated Nucleus of Sphygmomanometry Research.
What are holes in the surface of the dendrites or certain cells of the muscles and glands that are shaped to fit only certain neurotransmitters?
Neurotransmitter receptor sites on ligand-gated ion pores.
Is insulin cross blood brain barrier?
Insulin does crosses the blood brain barrier. Insulin crosses the blood brain barrier through the process of receptor-mediated transcytosis.
Opiate drugs occupy the same receptor sites as dopamine?
Dopamine is incorrect. Opiate drugs occupy the same receptor sites as endorphins.
Which type of membrane protein attaches to specific hormones such as insulin?
The membrane proteins that attach to specific hormones such as insulin are called receptor proteins.
Do t cells have receptor sites?
Yes.
What receptor sites does opiates lock into?
endorphins
What cells remove neurotransmitters from receptor sites?
Cells known as astrocytes can remove neurotransmitters from the receptor area.
How do substances work by altering the ways cells function?
Like the receptors for other protein hormones, the receptor for insulin is embedded in the plasma membrane. The insulin receptor is composed of two alpha subunits and two beta subunits linked by disulfide bonds. The alpha chains are entirely extracellular and house insulin binding domains, while the linked beta chains penetrate through the plasma membrane. The insulin receptor is a tyrosine kinase. In other words, it functions as an enzyme that transfers phosphate groups from ATP to tyrosine residues on intracellular target proteins. Binding of insulin to the alpha subunits causes the beta subunits to phosphorylate themselves (autophosphorylation), thus activating the catalytic activity of the receptor. The activated receptor then phosphorylates a number of intracellular proteins, which in turn alters their activity, thereby generating a biological response. Several intracellular proteins have been identified as phosphorylation substrates for the insulin receptor, the best-studied of which is insulin receptor substrate 1 or IRS-1. When IRS-1 is activated by phosphorylation, a lot of things happen. Among other things, IRS-1 serves as a type of docking center for recruitment and activation of other enzymes that ultimately mediate insulin's effects. from yo mama
Where is Leptin Secreted?
Leptin is a protein that is secreted from adipose (fat) cells. It acts on receptors in the Central Nervous System and other sites to induce energy expenditure and inhibit food intake (Margetic et al. 2002).
