Ponce De Leon sailed back to Florida in 1521, where the native Americans attacked him and his crew. Ponce De Leon was struck by an arrow and severly wounded. After what was left of the crew sailed back to Cuba, Juan Ponce De Leon died of his wounds soon after.
Juan Ponce de Leon, a Spanish explorer and conquistador, was the first person to create a settlement in Puerto Rico and he also helped lead the exploration of Florida. He is associated with the myth of the Fountain of Youth.