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Erwin Chargaff proposed two main rules in his lifetime which were appropriately named Chargaff's rules. The first and best known achievement was to show that in natural DNA the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units.

The second of Chargaff's rules is that the composition of DNA varies from one species to another, in particular in the relative amounts of A, G, T, and C bases. Such evidence of molecular diversity, which had been presumed absent from DNA, made DNA a more credible candidate for the genetic material than protein.

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11y ago
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15y ago

DNA composition: "Chargaffs rules" - varies from species to species

- amounts of 4 bases not equal

- bases present in characteristic ratio

humans:

A = 30.9%

T = 29.4%

G = 19.9%

C = 19.8% DNA composition: "Chargaffs rules" - varies from species to species

- amounts of 4 bases not equal

- bases present in characteristic ratio

humans:

A = 30.9%

T = 29.4%

G = 19.9%

C = 19.8%

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11y ago

Erwin Chargaff proposed two main rules in his lifetime which were appropriately named Chargaff's rules. The first and best known achievement was to show that in natural DNA the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units.

The second of Chargaff's rules is that the composition of DNA varies from one species to another, in particular in the relative amounts of A, G, T, and C bases. Such evidence of molecular diversity, which had been presumed absent from DNA, made DNA a more credible candidate for the genetic material than protein.

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10y ago

Erwin Chargaff was a notable biochemist who was born in Austria but later resided in America. Chargaff was best known for his discovery known as Chargaff`s rules in 1950. This states that in a DNA sample the amount of adenine and thymine will be equal as will the amount of guanine and cytosine. This is as a consequence of base pairing.

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11y ago

Developed Charagaff's rule which states the number of purines in DNA is equal to the amount of pyrimidines.

Example: G+A = T+C

(Purines) = (Pyrimidines)

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15y ago

he discovered that the four bases were adenine, thymine, guanine, and cytosine. that adenine was always connected to thymine and guanine is always connected to cytosine

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10y ago

Erwin Chargaff is best known for two rules he made in his field of study biochemistry. One of the rules states that the number of guanines and cytosine units in DNA are equal.

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