What does it mean when your mch is high?
Mean Corpuscular Hemoglobin (MCH) Normal Range: 26-34 pg (picograms/cell)
The mean corpuscular hemoglobin, or "mean cell hemoglobin" (MCH), is the average mass of hemoglobin per red blood cell in a sample of blood. It is reported as part of a standard complete blood count.
It is diminished in microcytic anemias and increased in macrocytic anemias.
It is calculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood. MCH=Hgb/RBC reference: http://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin
---- Macrocytic Anemia
* Types of macrocytic anemias ** 1.1 Megaloblastic anemias (DNA replication disorders) ** 1.2 Red cell membrane disorders producing codocytes ** 1.3 Alcohol ** 1.4 Association with rapid red cell turnover and reticulocytosis * Especially common causes of macrocytic anemias are the so-called megaloblastic anemias, in which cells are larger because they cannot produce DNA quickly enough to divide at the right time as they grow, and thus grow too large before division. Causes for the DNA synthetic problem range from lack of certain vitamins needed to produce DNA (notably folate and B12), to poisons or inhibitors of DNA replication, such as some kinds of antiviral drugs and chemotherapeutic agents.
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* Macrocytosis, sometimes without associated anemia, is often evident in persons with chronic alcoholism. Although the macrocytosis of alcoholism may be secondary to poor nutrition with a resulting folate or vitamin B-12 deficiency, it is more often due to a direct toxicity of the alcohol on the marrow. The macrocytosis of alcoholism usually reverses only after months of abstinence from alcohol. The remainder of the article can be seen on the following page