Leave out "nonfunctional" and you've got a more or less true statement.
Nonfunctional. Broken.
Nonfunctional zygote
Heartwood
hyoid bone
lyosomes
The air bag system did not pass self test at startup time and is nonfunctional. Lets hope it's just the fuse.
DefunctBrokenIn disrepair
front line ,team work
denatured
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Nothing gets added on to the DNA. Pol I is suppose to repair damaged sequences , so if it is nonfunctional, the damage sequences remain causing a mutated gene sequence.