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A "fix" is a dose of a drug to which you are addicted which one takes to stave off withdrawl symptoms. People who eat a lot of sugar can show symptoms of withdrawl if they are without it, and would need a "sugar fix" to avoid the withdrawl symptoms. Diabetics can also require a dose of sugar to quickly raise their blood sugar level if it is low.
But of course, people can talk about needing something as if they were addicted to it when they really aren't. In such a case, the "fix" is just something the person is craving.
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