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Amphetamines are psychostimulant

drugs of abuse and include methamphetamine, amphetamine and ecstacy

or MDMA. Amphetamine drugs can effect norepinephine in several ways. Initially amphetamine drugs will cause a massive release of all monoamine neurotransmitters (dopamine, serotonin and norepinephrine) from the vesicles inside the presynaptic

cleft of a neuron. Furthermore, amphetamine and methamphetamine (not MDMA) are very structurally similar to norepinephrine and can substitute, or move through, the norepinephrine transporter (NET) which regulates the amount of norepinephrine in the synapse. This can lead to dysregulation

of the transporter so that it no longer functions properly. This can happen in several ways including internalization of the transporter inside the presynaptic

cleft and/or phosphorylation of the transporter, which can essentially shut it off. This means that there is more norepinephrine in the synapse, which can bind to norepinephrine receptors and lead to the subjective (feeling), physiological, behavioral and neurobiological effects of amphetamine drugs.

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Q: What effect does amphetamines have on norepinephrine?
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What chemicals do amphetamines cause your brain to release?

Amphetamine is 1-phenylpropan-2-amine. Amphetamines are drugs that increase levels of the neurotransmitters norepinephrine, serotonin, and dopamine in the brain. They are commonly used as stimulants and appetite suppressants.


Does the effect of epinephrine mimic the effect of the sympathetic nervous system or the parasympathetic nervous system?

epinephrine (or adrenaline in the UK) mimics the effects of norepinephrine (noradrenaline in UK), so activates the SNS, not the PSNS.


Is it true that once the effects of a stimulant wear off the driver could quickly fall asleep?

That is true. Most stimulants work by binding to excitatory neurotransmitter receptors (such as the case with amphetamines), inducing the release of excitatory neurotransmitters (such as dopamine and norepinephrine, in the case of amphetamines), preventing the breakdown of excitatory neurotransmitters (as in the case of Ritalin, cocaine, etc.), or blocking inhibitory receptors (as in the case of caffeine). When this happens, the brain adjusts by reducing its sensitivity to its own excitatory neurotransmitters...especially in the case of adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine. So, once the stimulant wears off, the body is not only fatigued again, but is actually MORE sleepy than before...making it very easy to fall asleep.


Norepinephrine is known as what kind of messenger?

neurotransmitter


What are the three catecholamines?

Epinephrine, Norepinephrine, and Dopamine.

Related questions

Amphetamines have stimulating effects on the nervous system because they?

release norepinephrine


Amphetamines appear to exert their main effects by altering the release and reuptake of?

dopamine and norepinephrine


Amphetamines increase the release of what four chemicals in your body?

I only know of seratonin, dopamine, and norepinephrine (sp)


How do amphetamines work inside of the brain?

When amphetamines are activated they release something called norepinephrine. It also speeds up the heart and the metabolic process. The metabolic process transforms food to things the body can use.


What chemicals do amphetamines cause your brain to release?

Amphetamine is 1-phenylpropan-2-amine. Amphetamines are drugs that increase levels of the neurotransmitters norepinephrine, serotonin, and dopamine in the brain. They are commonly used as stimulants and appetite suppressants.


Do any cholesterol lowering drugs contain amphetamines?

No, there is no FDA approved drug for "cholesterol lowering" that contains amphetamines. It has no effect on cholesterol.


What has the author Scott E Lukas written?

Scott E. Lukas has written: 'Amphetamines' -- subject(s): Amphetamine, Amphetamine abuse, Amphetamines, Drug abuse, Drugs, Juvenile literature, Physiological effect, Toxicology 'Amphetamines (Encyclopedia of Psychoactive Drugs)' 'Amphetamines Danger in Fa'


Can drugs cause tremor as a side effect?

These drugs include amphetamines, antidepressant drugs, antipsychotic drugs, caffeine , and lithium.


What is secretes norepinephrine?

Norepinephrine is made from dopamine in the medulla of the adrenal gland.


Does the effect of epinephrine mimic the effect of the sympathetic nervous system or the parasympathetic nervous system?

epinephrine (or adrenaline in the UK) mimics the effects of norepinephrine (noradrenaline in UK), so activates the SNS, not the PSNS.


Preganglionic sympathetic fibers trigger the release of?

epinepherine and norepinephrine


What does norepinephrine do?

Norepinephrine is released from the sympathetic nervous system. Norepinephrine is a stress hormone which affects parts of the brain and causes the heart to beat more rapidly.