If a strong acid is mixed with a weak base, pH=pKa+/-1 in the buffer region.
Corrected:
If a strong base is mixed with a weak acid pOH= pKb +/-1 ( pH=(14 - pKb)+/-1) in the buffer region
[Remember: For one conjugated pair of weak acid (a = HB) AND its weak base (b = B-):
pKa + pKb = 14.0
and
pH + pOH = 14.0
pH meter
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It will be impossible to answer this question accurately without knowing what the questioner wants to determine.
The concentration of the buffer (the higher the concentration, the larger the buffering capacity) and how close the pKa of the buffer is compared to the pH of the solution (the closer the greater the buffer capacity).See the Related Questions to the left for more information on buffers.
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In general, you can look at the pKa (or pKb) of the weak acid (base), and go 1 pH unit above and below that for relatively efficient buffering. Of course, buffer capacity of the particular buffer in use will be important also.