The 2006 Ford Escape runs on regular unleaded.
The 2006 Ford Mustang runs on regular unleaded.
The 2006 Ford Focus runs on regular unleaded.
The 2006 Ford Fusion runs on regular unleaded.
The 2006 Ford Explorer runs on regular unleaded.
The 2006 Ford Expedition runs on regular unleaded.
The 2006 Ford Taurus runs on regular unleaded.
The 2006 Ford F-150 runs on regular unleaded.
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The 2006 Ford F-350-Super-DUTY runs on regular unleaded.
The 2006 Ford F-250-Super-DUTY runs on regular unleaded.
Yes, R134 is the only thing it can use.