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Mary j doesnt react with any known drug, so I suppose you might feel a slight difference in the high but lunesta is not a good drug for personal use, the best high you could expect is seeing very slight hallucinations in very dark rooms with a slight buzz. Ambien is a sleeping aid that has a more measurable euphoric high and is known to induce some intense hallucinations. Although both drugs seem to affect the dreaming experience. I wouldn't reccomend using drugs other than weed but these are the facts concerning your question.

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11y ago
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Q: What happens if you smoke weed and the take lunesta?
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