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What happens in deletion mutation?

Updated: 8/10/2023
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13y ago

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"A type of gene mutation wherein the deletion (as well as addition) of (a number of) nucleotide(s) causes a shift in the reading frame of the codons in the mRNA, thus, may eventually lead to the alteration in the amino acid sequence at protein translation."

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13y ago
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13y ago

In a deletion mutation, an entire base pair (or many base pairs) is removed from the DNA sequence.

For Example: (5')AGATAGA(3') would become (5')GATAGA(3') if the first adenine is removed.

Deletion mutations that occur in non-coding DNA or the third base pair of a codon, are usually tolerable by the cell. Deletion mutations that cause frameshifts are usually fatal.

For example the codon sequence of a DNA strand could be:

AUG TAG ATA But after a deletion, of the second guanine,

AUG TAA TA_ The entire sequence downstream of the mutation has shifted by one base pair and will code for the incorrect amino acid.

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11y ago

Entire sequences of nucleic bases are left out due to error when DNA is being copied.

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13y ago

Chromosome: When a part of the chromosome is removed

Genetic: When one or more bases (ATCG) are removed from the portion of DNA

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14y ago

Deletion mutation is when a chunk of the DNA is removed, so for example: ATGCCG[TATAG]CCGATGC if the area in brackets is removed then the DNA strand changes to ATGCCGCCGATGC

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12y ago

this isn't the place to look. I don't know.

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11y ago

loss or addition of nucleotide/s in the gene with frame shift causing abnormal function

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13y ago

one of the genes is missing

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Q: What happens in deletion mutation?
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