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When a migraine happens - there are a host of changes across the entire body. Migraines cause a "spreading cortical depression," which is just a way of saying that a wave of lowered activity spreads across a certain area of your brain. When it reboots, nerves go haywire, blood vessels dilate in the brain. For some people, the digestion halts to a slow or stop - called gastroparesis. This is what is to blame for the cyclical vomiting people will have.

Some people will notice a day or two before their migraine hits that they are experiencing mood changes, or urinating more. This is a sign of that cortical depression in effect.

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16y ago
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11y ago

Migraine is a genetic neurologic disease or which pain is only one possible (not necessary) symptom. We don't understand all the details of what happens during a Migraine yet, but new research has shown:

  • Although blood vessels may often be involved in the Migraine process, it is not a vascular disorder
  • Many brain chemicals may play a part in Migraine. Too much or too little of a chemical may trigger an attack
  • Cortical spreading depression is a slow moving wave of electrical activity that *flows* across the surface of the brain, creating disturbances we know as aura
  • Inflammation often plays an important part in the Migraine process.
  • Although the brain itself has no pain perception, the blood vessels and nerves that run through the brain do, as well as the dura mater which covers the brain, is thought to be part of the reason we suffer pain during the majority of Migraine attacks.
  • Central sensitization which occurs in the brain can make the patient feel pain without normally painful stimulation. This is called allodynia.

For appropriate diagnosis, treatment and prevention of headache disorders, seek the help of a board certified headache specialist.

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14y ago

Blood Vessels HURT!!!!! LOL

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11y ago

It gets tight so it hurts

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12y ago

It hurts

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Q: What happens in your head when you have a headache?
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