What is Arndt-Schultz law?

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2008-03-20 00:40:33

[The Arndt-Shultz Law is very well described, with history and

examples, by Dr. Rajneesh Kumar Sharma on Additional data is provided

by Dr. A. B. Ram Jyothis on] The

Arndt-Shultz Law summarizes experiments which measure the

physiological response of a living organism to a stimulus. It says

a small amount of a chemical or electrical or laser or other

stimulus will increase physiological activity, a large amount of

the same stimulus will kill cells of the organism, and an

intermediate amount will inhibit physiological activity. In brief:

the physiological response reverses direction when the stimulus

changes from small (weak) to large (strong), and vice-versa. An

example of the Arndt-Shultz Law in action is the 1944 observation

that a large dose of penicillin will kill a Staphylococcus

infection, while a small dose will stimulate its growth. The

Arndt-Schultz Law applies only where there is a dose-dependent

reversal of the physiological effect on an organism, from

beneficial to harmful, or vice-versa. In the case of Vitamin C, the

reversal has occurred by the time the dose causes bowel

intolerance. In the case of radiation in the environment from

cosmic rays or nuclear fission or from decay of radioactive

materials, in the development of protective standards, it was

assumed by the U.S. Environmental Protection Agency and the U.S.

Atomic Energy Commission that zero radiation is the only beneficial

level of radiation. This assumption is contrary to the evidences

that support the Arndt-Schultz Law. Submitted by David Langford, 18

March 2008.

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