Groat's syndrome is a fictional neurological disorder (as discussed in "Curb Your Enthusiasm," Season 2, Episode 5).
This hypothetical diseases is marked by hyperactivity "Like after 5 cups of coffee," and it was named after the fictitious doctor in the show who first diagnosed it.
There is Land's End in the south and John o' Groats in the north.Land's End to John o' Groats is a journey - the traversal of the whole of the island of Great Britain from southwest to northeast. * Land's End is the extreme southwestward (but not southern or western) point of Great Britain, situated in western Cornwall at the end of the Penwith Peninsula. * John o' Groats is the traditionally acknowledged extreme northern point of Scotland, in northeastern Caithness. The actual northernmost point is at nearby Dunnet Head. The point which is actually furthest by road from Land's End is Duncansby Head, about 2 miles from John o' Groats.
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