Leukoesterase = Leukocyte + Esterase. Leukoesterase is a combination word derived from the words Leukocyte and Esterase (LE), which is a urine test for the presence of white blood cells in the urine. "Leukocyte" meaning white blood cell and "Esterase" meaning white blood cell enzyme. Leukoesterase is released by white blood cells. A positive screen for leukoesterase usually indicates a urinary tract infection, in combination with a positive nitrite test - (see "Nitrite Test"). The LE test is also used to screen for gnorrhea and amniotic fluid. In a normal urinalysis Leukesterase is not present or "negative" when listed in lab results. *Please see Leukocyte Esterase Wiki for further discussion and more detailed explantion.