Leaves the presynaptic neuron, activates ion channel
a neuron
Facilitation
Presynaptic neurons release the neurotransmitter in response to an action potential. Postsynaptic neurons receive the neurotransmitter (and can however become presynaptic to the next nerve cell, if the neurotransmitter has stimulated the cell enough).
yes
Presynaptic membrane
Your question isn't very clear.... Presynaptic knob is the neurone before the synapse. Postsynaptic knob is the neurone after the synapse. Calcium ions diffuse into the presynaptic knob down their concentration gradient when an impulse arrives at the presynaptic knob. This causes the vesicles to move towards the presynaptic membrane and fuse with it. This releases the neurotransmitter (e.g. Ach). The Ach diffuses down their concentration gradient in the synaptic cleft then binds with receptors on the post synaptic membrane. This binding causes the Na+ ion channels to open, and the influx of Na+ ions causes depolarisation, and a new action potential in the postsynaptic knob. Then the acetate and choline diffuses back into the presynaptic membrane and is recombined using ATP.
They don't, the neurotransmitters stay on either side of the synapse. Neurotransmitters are released when the synaptic vesicles fuse with the presynaptic neuron's membrane, so as to release them into the synaptic cleft.
Terminal Button
Sodium ions
acetylcholine is released from presynaptic neurons in response to a nerve impulse
Presynaptic neuron sends postsynaptic receives