A treppe is a gradual increase in muscle contractions following rapidly repeated stimulation. When a muscle is stimulated a second time immediately after the first , the next muscle will be higher in intensity.
•Increased contraction in response to multiple stimuli of same strength
When the contractile frequency is increased, cardiac output is elevated through an increased number of beats per minute, as during exercise. In most species, including nonfailing human myocardium, increased frequency also leads to elevation of contractile force, an event also known as the Treppe phenomenon or the Bowditch effect (Miura et al. 1992). However, in the failing myocardium, frequency potentiation of contractile force is inverse, decreasing contractile force. The Treppe phenomenon has been suggested to result from increased transsarcolemmal Ca2+ influx leading to greater filling of the SR and therefore, a higher amount of Ca2+ available for release during systole (Pieske et al. 1995). This positive inotropic effect can be further augmented with ß-AR agonist dobutamine under resting conditions, when the heart rate is modulated by pacing (Kambayashi et al. 1992). In failing hearts, SR Ca2+ uptake was significantly reduced, suggesting a possible mechanism for inverse force-frequency relationship in CHF (Pieske et al. 1995). Altered Ca2+ handling could be explained by a depressed role of SERCA combined with enhanced cytosolic Ca2+ extrusion via NCX (Pieske et al. 1999b).== == When the contractile frequency is increased, cardiac output is elevated through an increased number of beats per minute, as during exercise. In most species, including nonfailing human myocardium, increased frequency also leads to elevation of contractile force, an event also known as the Treppe phenomenon or the Bowditch effect (Miura et al. 1992). However, in the failing myocardium, frequency potentiation of contractile force is inverse, decreasing contractile force. The Treppe phenomenon has been suggested to result from increased transsarcolemmal Ca2+ influx leading to greater filling of the SR and therefore, a higher amount of Ca2+ available for release during systole (Pieske et al. 1995). This positive inotropic effect can be further augmented with ß-AR agonist dobutamine under resting conditions, when the heart rate is modulated by pacing (Kambayashi et al. 1992). In failing hearts, SR Ca2+ uptake was significantly reduced, suggesting a possible mechanism for inverse force-frequency relationship in CHF (Pieske et al. 1995). Altered Ca2+ handling could be explained by a depressed role of SERCA combined with enhanced cytosolic Ca2+ extrusion via NCX (Pieske et al. 1999b).== ==
Das Mädchen auf der Treppe was created in 1982.
Die Treppe - 1950 is rated/received certificates of: West Germany:16 (f)
The cast of Die Treppe - 2005 includes: Martin Ihm as Polizeikommissar Andreas Kneller
Stairs is "die Treppe"
Die Treppe - Jenseits der Angst - 2003 is rated/received certificates of: Austria:12
Schritt Stufe Treppe Maßnahme Tritt
•Increased contraction in response to multiple stimuli of same strength
The cast of Der Rowdy auf der Treppe - 1970 includes: Eva Kerbler as Joyce Michael Toost as Mike Kurt Weinzierl as Wilson
Treppe
Nach oben, or just oben To go upstairs - die Treppe hinauf gehen
The cast of Isabel auf der Treppe - 1984 includes: Irina Gallardo as Isabel Horst Hiemer as Opa Kunze Ruth Kommerell as Frau Flickenschildt Teresa Polle as Rosita Perez Jaecki Schwarz as Dieter Kunze
the four phases of temporal summation are : fatigue, incomplete tetanus, treppe & complete tentanus.