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Megakaryocyte
megakaryocyte
This is known as a megakaryocyte.
The precursor cell to blood platelets are megakaryocyte precursor (MkP) cells in the bone marrow.
Hematopoietic stem cellprecursor cells in the bone marrow when reaches megakaryocyte stage it loses its ability to divide.Once the cell has completed differentiation and become a mature megakaryocyte, it begins the process of producing platelets.
Megakaryocyte is a bone marrow cell. This cell is responsible for the production of blood thrombocytes, also known as platelets. These platelets are necessary for blood clotting.
Platelets, also known as thrombocytes or megakaryocyte fragments, are responsible for blood clotting.
Platelets are pieces of a larger cell called a megakaryocyte. They are not individual cells.
largest cell found in the bone marrow, and it forms platelets by shedding pieces of its cytoplasm (also called "cytoplasmic fragmentation").
Another said that it is a bizarre Multinucleate Cell called a Megakaryocyte. Also we find - Myeloid Stem Cells.
Magakaryocytes are normally found only in the bone marrow, releasing their contents (platelets) into the blood. However, in certain disorders, MDS for example, they can be found abnormally in the blood (in this case as micromegakaryocytes).
The megakaryoblast undergoes endomitoses (the nucleus becomes polyploid and the cell does not divide) and ultimately develops into megakaryocyte. The successive stages are Megakaryoblast -> Promegakaryocyte -> Megakaryocyte Megakaryocyte produces thrombocytes, that is fragments of megakraryocyte' cytoplasm.