Doxofylline Pka value is about 9.8.
pKa = 15
It is around pKa=13
The pka of a protonated ether (the conjugate acid) is about -3.5
7.6
There are two answers: bicarbonate has two pKa's - because bicarbonate can gain a proton to become carbonic acid or lose a proton to become carbonate. Two reactions; two pKa's. The pKa for bicarbonate carbonic acid reaction is 6.4 The pKa for bicarbonate carbonate reaction is 10.3 Both pKa's are temperature sensitive.
No.
Doxofylline Pka value is about 9.8.
pKa = 15
It is around pKa=13
By following + or - 2 pH to the pKa value
The pka of a protonated ether (the conjugate acid) is about -3.5
The conjugate acid is Hydrogen (H2), the pKa of which is 35.
3.3
7.6
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
pKa = 6.36 of carbonic acid to HCO3-