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The antonym for Despite certainly is not "in spite of." That would be a synonym. As would be "notwithstanding." The opposite of despite would be closer to because of, or on account of.

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12y ago
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13y ago

The word "despite" has the same meaning as "in spite of", and synonyms would be notwithstanding or regardless (although they require different sentence forms).

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11y ago

in spite of, regardless, notwithstanding

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13y ago

hence

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Q: What is a synonym for despite?
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