The quickest and shortest route is I-5 North.
You need to take I-80 E towards Sacremento. It'll take about a day to drive it.
Route-66 is the best driving route from Los Angeles to Ontario Canada
route 66
On an airplane.
a road
use the 5
I-5 South
E842 is the best route across. SS16 to A14 connects to that.
I would take Ca-99 down to Ca-120 and ultimately towards Yosemite National Park. It'll be a 160 mile drive and take about 3 hours and 30 minutes.
Take I-8 WEST to I-5 NORTH to LOS ANGELES via I-805 NORTH around San Diego (EXIT 6B off I-8).Take I-5 NORTH to Los Angeles.
Interstate - 5.
Take I-10 WEST to Los Angeles.