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Both Tylenol 3's and vicodin contain acetaminophen (APAP), an NSAID pain reliever. The more powerful ingredient in Tylenol 3 is codiene; whereas the powerful painkiller in vicodin is hydrocodone. Overall, hydrocodone is a lot more effective than codeine as a painkiller. Moreover, codeine is a pro-drug; a drug that only becomes effective when your system changes it into morphine. As there is a limit to how much codiene your system can convert in any given amount of time, there is an effective max dosage that you can't exceed even if you take more of the medication. Being a drug, hydrocodone has no such inherent limit.
Vicodin is a preparation of acetyl-para-aminophenol, often abbreviated APAP, (the active ingredient in Tylenol), and hydrocodone, a semi-synthetic opioid analgesic about six (6) times stronger than codeine or about 60% the strength of and equivalent amount of morphine.

Tylenol with codeine is exactly what it sounds like. It is a preparation of Tylenol (APAP) and codeine. Codeine is a weak, naturally occurring opioid of about 10% the strength of an equivalent amount of morphine.

Both Vicodin and Tylenol with codeine are used to relieve moderate postoperative pain, such as might be associated with oral surgery for instance. Like all opioids, codeine and hydrocondone are addictive and poisonous in excessive dosages (overdose). When using these medicine for instructions closely. Opioids are addictive, compulsion forming, are toxic in overdose, and have a relatively narrow therapeutic range (the difference between and effective dose and a toxic dose) and therefore should not be self-administrated, but should only be taken under the prescription of a physician.

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10y ago
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10y ago

Tylenol #2: 300mg Acetaminophen w/ 15mg Codeine and 15mg Caffeine.

Tylenol #3: 300mg Acetaminophen w/ 30mg Codeine and 15mg Caffeine.

Additionally...

Tylenol #1: 325mg Acetaminophen w/ 8mg Codeine and 15mg Caffeine (sold in Canada w/o Rx)

Tylenol #4: 300mg Acetaminophen w/ 60mg Codeine.

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10y ago

Vicoden: Mixture of Hydrocodone relieves pain. Acetaminophen is a less potent pain reliever. Tylenol 3: Mixture of codeine relieves pain. Acetaminophen is a less potent pain reliever.

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12y ago

They are different compounds (codeine vs. hydrocodone), so it's difficult to compare them. However, Vicodin is probably more effective as a pain reliever.

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11y ago

Vicoprophen has IBU and hydrocodone, and Tylenol 3 has Codein and acetaminophen

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Q: What is the difference between Tylenol 2 and Tylenol 3?
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