Helicase unwind the two DNA strands while topoisomerase unwind and also rejoin the the two strands of DNA.
HaeIIIrestriction enzymes
one of them is heliocase. it 'unzips' the DNA strand. You can always remember this because it's in a popular joke: Q. Why is the enzyme heliocase a lot like a teenage boy? A. They both want to unzip your jeans (genes) !!!!!
DNA Helicase - responsible for separating the two stands DNA Polymerase - responsible for catalyzing the addition of bases to the new strand DNA Ligase - responsible for sealing fragments
The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively
DNA Helicase is the enzyme responsible for unzipping DNA before replication occurs.
Helicases and gyrases both function to uncoil the supercoiling of the two DNA strands. Moreover, gyrase is responsible for adjusting the tension in the two strands so that they don't snap while unraveling.
HaeIIIrestriction enzymes
one of them is heliocase. it 'unzips' the DNA strand. You can always remember this because it's in a popular joke: Q. Why is the enzyme heliocase a lot like a teenage boy? A. They both want to unzip your jeans (genes) !!!!!
Yes, it unwinds the DNA double helix prior to transcription/protein synthesis and DNA replication.
Topoisomerase
DNA Helicase - responsible for separating the two stands DNA Polymerase - responsible for catalyzing the addition of bases to the new strand DNA Ligase - responsible for sealing fragments
The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively
Helicase
Enzyme helicase unwinds the DNA by breaking the bonds between nucleotides. Thus attaches itself at the nucleotides.
DNA Helicase is the enzyme responsible for unzipping DNA before replication occurs.
Helicase splits the 3' and 5' Okazaki fragments, while the DNA polymerase attaches the "new" 3' nucleotide, with the "old" 5' nucleotide. As well as proofreading, or making sure that the bases are complementary in order to avoid mutations.
DNA is, as you say, "unzipped" is a complex process. DNA usually unwinds either to replicate DNA or synthesize mRNA to make proteins. I'll use DNA replication as the example. when the process starts, it will start at hundreds of sites along the length of the DNA molecule. once started the replication will proceed in both directions. DNA helicase is the enzyme that opens the two strands, and the enzyme topoisomerase is before helicase to make sure no tension builds up as the strands unwind. after topoisomerase runs down the length, closely followed by helicase, binding proteins stick to the newly opened nucleotides to prevent the strands from sticking together. that's the first basic step of DNA replication and basically answers your question. Helicase opens it, but remember it must be triggered by a enzyme of protein in order for it to start, and then continues until the molecule is finished.