310 miles
It is 425 miles from Tampa to the Florida Keys.
Bout this long <-------->
The Keys are 120 miles long. St. Petersburg to Key West is 410 miles.
The Keys are 120 miles long. Tampa to Key West is 425 miles.
About 233 miles
The Keys are 120 miles long. Tampa to Key West is 425 miles.
The Keys are 120 miles long. Orlando to Key West is 393 miles.
The answer to such a question depends on your ultimate destination in the Florida Keys. For instance, depending on the exact route, the distance between Tampa and, say, Key Largo (the northernmost island in the Florida Keys) can range from 295 to 325 miles. Meanwhile, the distance between Tampa and Key West (which is located at the southern end of the Florida Keys) can range from 400 to 425 miles.
The Keys are 120 miles long. Tampa to Key West is 425 miles.
St Petersburg, The Florida keys and anywhere in Marco Island!
Orlando to Key West is 393 miles. The Keys are about 120 miles long.
The Keys are 120 miles long. Philadelphia to Key West is 1355 miles.