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299 miles taking this route:
- Take I-75 SOUTH from Ft. Myers to Florida's TURNPIKE (toll) SOUTH to KEY WEST at EXIT 5, outside of Miami.
- Take Florida's Turnpike (toll) SOUTH to U.S. 1 SOUTH to KEY WEST at END Florida's Turnpike in HOMESTEAD.
- Take U.S. 1 SOUTH to Key West.
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What is the driving distance from Fort Myers FL to Key West FL?
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What is the driving distance from fort Myers to key west?
300 miles.
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