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About 1,900 miles of that 2,006 mile trip can be effectively driven on I-40 much of which is the old US Route 66. This is the route in detail:

  1. Take I-40 WEST through Tennessee, Arkansas, Oklahoma, Texas, New Mexico and Arizona to I-15 SOUTH in Barstow, California.
  2. Take I-15 SOUTH to I-10 WEST to Los Angeles at EXIT 109A.
  3. Take I-10 WEST to Los Angeles.
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Q: What is the fastest driving route from Nashville to Los Angeles?
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