The Great Lakes are a collection of five freshwater lakes, The Great Salt Lake is one saltwater lake. The Great Lakes are much larger than the Great Salt Lake. (The Great Lakes cover 80,545 square miles, the Great Salt Lake covers between 1,000 and 3,000 square miles, depending on the rainfall.)
There are several lakes in the United States, including the Great Lakes. The three large lakes other than the Great Lakes are: The Great Salt Lake, Lake of the Woods, Iliamna Lake, Lake Oahe, and Lake Okeechobee.