The opposite gender of sir is Madam.
In common language, the opposite term for sir is madam.
If you are using 'Sir' as a title (a knighted person), there are number of paired sex based honorifics for "Sir" :
When using 'sir' as a simple polite title as found on a letter or used to address a stranger:
However a sex difference does not make the word opposite. Considering that "sir" is an honorific, it positions the person being talked to as superior (in some way) to the talker, the opposite would be a form of address that implies the speaker is superior to the person being talked to. In Shakespearian plays this is handled with the word "sirrah" (e.g. Now, knock when I bid you, sirrah villein! The Taming of the Shrew: I, ii ). This quote also introduces another potential opposite for "sir" which is "villein". This word means a person of low estate who is morally disreputable or who is at the low end of the social scale (a peasant).
Madam,lady,woman,girl
Lady
Sir
What is opposite of god
madam
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Madem
Ma'am
Clot is not gender specific.
The opposite gender of fraternity is sorority.
The opposite of dairymaid is dairyman.
Cock's opposite gender is hen.
Mistress is the opposite gender of master.
The opposite gender of dame is sir - used as a title bestowed on a woman.(e.g. Dame Margot Fonteyn, Sir Walter Raleigh) If it is the honour itself - she was made a dame in the honours list - the opposite is knight.The opposite gender of the slang term dame (woman) is "guy."
Doctor is a neuter gender
Clot is not gender specific.
An emperor is the opposite in gender to an empress.
Opposite gender of Filipino: Filipina
The opposite gender of fraternity is sorority.
The opposite gender of giantess is giant.
Opposite gender to negro is-- NEGRESS
The opposite gender is girl.
The opposite of dairymaid is dairyman.
A Printe is the opposite gender of Printecess
Cock's opposite gender is hen.