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What is the risk associated with vaccines prepared from dead or weakened pathogenic microbes?
Wiki User
∙ 14y ago
In the US there are two types of vaccines approved for the seasonal flu, a vaccine for injection into the muscle and a vaccine mist for spray into the nose. The side effects are different depending on which you use. The mist is only available to healthy people age 2 - 49. The shots are approved for use in anyone 6 months old and over unless there are Allergies that prevent their use. Infants under 6 months old can not be vaccinated until they are older.
The shots use a dead virus and the nasal mist is made with attenuated (weakened) viruses that can't make you sick if you have an otherwise normal immune system.
They are made exactly like they have been made for decades with an exceptionally good track record of low incidence of adverse effects or allergic reactions.
Life-threatening allergic reactions to vaccines are very rare. If they do occur, it is usually within a few minutes to a few hours after the vaccination. It is recommended that you report to the nurse before you receive the vaccination if you have any medication or food allergies (especially to eggs or chicken).
The most commonly reported side effects of thenasal mist include:
- Some children and adolescents 2-17 years of age have reported mild reactions, including: runny nose, nasal congestion or cough; fever; headache and muscle aches; wheezing; abdominal pain or occasional vomiting or diarrhea.
- Some adults 18-49 years of age have reported: runny nose or nasal congestion; sore throat; cough, chills, tiredness/weakness; headache.
The most frequently reported side effects of the flu shots are:
- Mild hypersensitivity reactions (such as rash).
- Local reactions at the injection site such as tenderness, redness, swelling, pain or soreness.
- The most common systemic adverse reactions were headache, malaise, and muscle aches. Fever is rare, but a very mild fever is possible the first day or two.
In 1976, an earlier type of inactivated Swine Flu vaccine was associated with cases of Guillain-Barré Syndrome (GBS). There has not been any link to GBS with the use of the nasal mists.
The shots are made an entirely different way now than they were made in the 1970's. The new way has been proven for over 30 years.
Wiki User
∙ 14y ago
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What is the role that microorganisms play in vaccine production?
Microorganisms can be used as vaccines. Some microbes can be genetically engineered to produce components of vaccines.
How can genomic sequencing help to develop vaccines?
By the process which scientists look at and try to understand the genetic instructions of disease-causing microbes, in other words DNA created vaccines.
Are the microbes that are injected in a vaccination dead or alive?
They can be either. Some vaccines are made with dead viruses or particles of viruses and other vaccines are made with attenuated (weakened) viruses that are not able to make an otherwise healthy person sick. In 2009 the swine flu vaccine approved for use in the US was prepared both ways, the nasal flu vaccine was made from attenuated viruses and the shots were made with dead viruses.
Are vaccines only used for viruses?
I'm not an expert, but from what I can gather, vaccinations are used for both virus' and pathogenic bacteria (harmful bacteria). Vaccines contain a section/segment of the virus or bacteria (for example a flagella) to infect the body. The body then produces memory cells so that the body has an immunity against the virus or bacteria (note that this immunity may not last a lifetime).
What are cell culture based vaccines?
cell culture vaccines are vaccines produced from cells that are cultured and grown under controlled conditions.
What does vaccine and pathogenic have in common?
Vaccines are for preventing infections. Infections are pathogenic (caused by germs). Vaccines help your body prepare to fight specific pathogens, e.g., bacteria and viruses.
What are Two groups of microbes?
vaccines and antibiotics
What is the classification of vaccines that include tetanus and diphtheria?
pathogenic toxins
Name two groups of medicine used by doctors to fight microbes?
Doctors use vaccines to fight microbes on a long term scale. They use antibiotics to fight them on a short term scale.
What is the role that microorganisms play in vaccine production?
Microorganisms can be used as vaccines. Some microbes can be genetically engineered to produce components of vaccines.
Definition of the conventional vaccines?
Conventional vaccines consist of whole pathogenic organisms, which may either be killed or live vaccines; the virulence of pathogens is greatly reduced in attenuated vaccines. This is classified into 2 categories :a)Live or attenuated vaccines; (eg : BCG vaccine)b)Inactivated vaccines (eg : Salk polio & Pertussisvaccines)
Are Influenza vaccines prepared from blood products?
No, they are made from the virus
How can genomic sequencing help to develop vaccines?
By the process which scientists look at and try to understand the genetic instructions of disease-causing microbes, in other words DNA created vaccines.
What are the vaccination types?
Killed vaccines: These are preparations of the normal (wild type) infectious, pathogenic virus that has been rendered non-pathogenic, usually by chemical treatment such as with formalin that cross-links viral proteins.Attenuated vaccines: These are live virus particles that grow in the vaccine recipient but do not cause disease because the vaccine virus has been altered (mutated) to a non-pathogenic form; for example, its tropism has been altered so that it no longer grows at a site that can cause disease.Sub-unit vaccines: These are purified components of the virus, such as a surface antigen.DNA vaccines: These are usually harmless viruses into which a gene for a (supposedly) protective antigen has been spliced. The protective antigen is then made in the vaccine recipient to elicit an immune response
Are the microbes that are injected in a vaccination dead or alive?
They can be either. Some vaccines are made with dead viruses or particles of viruses and other vaccines are made with attenuated (weakened) viruses that are not able to make an otherwise healthy person sick. In 2009 the swine flu vaccine approved for use in the US was prepared both ways, the nasal flu vaccine was made from attenuated viruses and the shots were made with dead viruses.
What is the importance of immunisation and the vaccines given?
To get your immune system prepared if the same pathogens attack your body again.
What is attenuated flu vaccine?
Attenuated simply means "weakened". An attenuated flu vaccine refers to vaccines made with live viruses (so you get a good immune response), but they have been weakened chemically so that they are unable to give you the flu. There are two types of flu vaccines available in the US. What is called inactivated, inactive or "dead" vaccine and what is called "live", weakened/attenuated vaccine. The injectable vaccines (intradermal and intramuscular) are made with "dead" viruses and the nasal spray is made with "live" attenuated viruses.
