As an ex pharmacy tech...amoxicillin is one of the fast movers in the pharmacy it's quite difficult to check it's shelf life but we normally try to keep anti bi for up to one year , 2 years for the most but if it's mixed 10 days ..and it should be on the shelf THROW OUT your amoxicillin! For two reasons: ALL antibiotics should be taken until the bottle is empty. If there are some left over, whoever took it 4 years ago, didn't finish it, which can mess up your immune system. PLUS, if you take it now even if it were good, you won't get the full dose. AND it's NOT good! P.S. To dispose of old pills, DO NOT FLUSH THEM or just throw them out: check with your municipality about local medication disposal so you can keep the chemicals out of the general water supply and/or food chain. Many recycling centers have dedicated collection days. Shelf life is generally one year.D Studies show that expired drugs may lose some of their potency over time, from as little as 5% or less to 50% or more (though usually much less than the latter). Even 10 years after the "expiration date," most drugs have a good deal of their original potency. If your life does not depend on an expired drug - such as that for headache, hay fever, or menstrual cramps - take it and see what happens. One of the largest studies ever conducted that supports the above points about "expired drug" labeling was done by the U.S. military 15 years ago, according to a feature story in the Wall Street Journal (March 29, 2000), reported by Laurie P. Cohen. Here are a couple of resources as well: https://www.health.harvard.edu/fhg/updates/update1103a.shtml http://www.baliadvertiser.biz/articles/paradise/2006/expired_drugs.html
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