Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to 5th Avenue-53rd Street. Then walk 1 block west on 53rd Street to 6th Avenue.
You'll know which way is west because 5th Avenue is the dividing line between the West and East Sides. So on the west side of 5th Avenue, the street sign will say "West 53rd Street," while on the east side of 5th Avenue, it will say "East 53rd Street."
Take the Uptown 1 train (of the 1-2-3, the red line) from the end of the line, South Ferry (at the intersection of State and Whitehall Streets) to 34th Street-Penn Station. Transfer at Penn Station to the Uptown E train (of the A-C-E, the blue line) to 53rd Street-5th Avenue.
It depends on where you're coming from, but the E train (of the A-C-E, the blue line) stops at 5th Avenue and 53rd Street.
The only subway station nearby is the 86th Street station (at Lexington Avenue) on the 4-5-6 (the dark green line).
Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to 53rd Street-5th Avenue. Fifth Avenue is one block west of Madison Avenue.
Yes, you can take the E from Jamaica Center to 53rd Street-Lexington Avenue or 53rd Street-5th Avenue.
Walk west to Lexington Avenue and north to 53rd Street, and take the Downtown E train (of the A-C-E, the blue line) from Lexington Avenue-53rd Street to 34th Street-Penn Station.
Take the Uptown 6 train from 33rd Street (at Park Avenue South, 1 block east of Madison) to 51st Street.The 51st Street station on the 6 train is connected to the Lexington Avenue-53rd Street station on the E and M trains, so you can transfer without exiting the subway system.Transfer to the 53rd-Lexington station, and take the Downtown E train 2 stops to 7th Avenue (at 53rd Street) or to the next stop, 50th Street (at 8th Avenue). The walk is about equidistant from each station: 3 street blocks or 1 avenue block.
Take the Downtown E train (of the A-C-E, the blue line) from 5th Avenue-53rd Street to 50th Street.Transfer at 50th Street to the Uptown C train, and take the Uptown C to 110th Street-Cathedral Parkway.You will exit the subway at the northwest corner of Central Park, at the corner of Central Park West and Central Park North (aka 8th Avenue and 110th Street).Walk three avenue blocks west to Amsterdam Avenue: 8th Avenue/CPW ---> Manhattan Avenue ---> Columbus Avenue/Morningside Drive (Columbus becomes Morningside Drive at 110th Street) ---> Amsterdam Avenue, and then three blocks north to 113th Street.You will probably want to walk west first, since if you walk north to 113th first, you'll have to cut across Morningside Park, which will be somewhat of a detour.
Tiffany and Co. is located at 727 Fifth Avenue, at the southeast corner of 57th Street. Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to 5th Avenue-53rd Street. Then walk 4 blocks up Fifth Avenue to 57th Street.
From Penn Station in New York, you can take the Uptown R, N or W train and get off at the Fifth Avenue stop. You can then walk down Fifth Avenue to 53rd Street which is where F.A.O. is located.
The closest subway stations are the 5th Avenue-53rd Street station on the E train (of the A-C-E, the blue line) and M train (of the B-D-F-M, the orange line), the 5th Avenue-59th Street station on the N-R-Q (the yellow line), and the 51st Street station (at Lexington Avenue) on the 6 train (of the 4-5-6, the dark green line).Lexington is 2 blocks east of Madison, and 5th is 1 block west of Madison.
The American Girl store is at the corner of 5th Avenue and 49th Street. Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to 5th Avenue-53rd Street. Then walk 4 blocks down 5th Avenue to 49th Street.
The address 198 East 76th Street is at the corner of 3rd Avenue. Take the Downtown 6 train (of the 4-5-6, the dark green line) from 77th Street (at Lexington Avenue, which is one block west of 3rd Avenue) to 51st Street.The 51st Street Station on the 6 train is connected to the Lexington Avenue-53rd Street Station on the E train (of the A-C-E, the blue line) and the M train (of the B-D-F-M, the orange line), so you can transfer without exiting the subway system.Transfer to the Downtown E train, and take the Downtown E from Lexington Avenue-53rd Street to 34th Street-Penn Station.
Walk down to 53rd Street and Lexington Avenue. Take the Downtown E train (of the A-C-E, the blue line) from Lexington Avenue-53rd Street to 50th Street.Transfer at 50th Street to the Uptown C train to 81st Street-Museum of Natural History.If you're traveling on a weekday, you can skip an unnecessary stop by getting off the E at the stop before 50th Street, which is 7th Avenue-53rd Street (usually just called the 7th Avenue stop).Transfer at 7th Avenue to the Uptown B train (of the B-D-F-M, the orange line) to 81st Street-Museum of Natural History.However, the B only runs on weekdays.
Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to 5th Avenue-53rd Street. Then walk 2 blocks south on 5th Avenue to St. Patrick's (on 5th Avenue between 51st and 50th Streets).