1995 Nebraska-52.4/game. Including 62 against Florida's #2 ranked defense in the national title game.
As of November 11, 2011 the current Houston Cougars average 54.7/game through 10 games. In order to best Nebraska's all-time record, Houston would need to average 47/game during their last two regular-season games plus the potential Conference USA championship game and bowl game. In the event that Houston doesn't qualify for the conference title game, they would need to average about 45.2/game (two regular season games plus bowl game).