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Lock and Key to the Nth Degree. When any one of 'very many' intercellular 'blood borne' Activating Factors finds & fits-to a Cell Surface Receptor, this causes conformational changes to the 'Transmembrane Signal Proteins' that rapidly become apparent on the cytoplasmic 'side' of the cell membrane as another signal or set of signals, usually directed to the Nucleus.

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13y ago
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12y ago

All hormones have "target cells" upon which they initiate an physiological action. A perfect example is Parathyroid Hormone (PTH). When plasma calcium is low, PTH is stimulated and secreted from the parathyroid gland, and in concert with vitamin D, triggers osteoclasts in bone to initiate bone resporption to raise plasma calcium. In order for this to happen, the hormone has to bind to very specific receptors (usually protein orcarbohydrate macromolecules) on that target cell surface to initiate the action.

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12y ago

Water-soluble hormones. Insulin and epinephrine

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12y ago

the lipid soluble hormone and water soluble hormones, bind to receptor protein to reach the target cell.

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Q: Do hormones bind receptors at the target cells?
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What are the structures that allow hormones to bind to their target cells?

Receptors allow hormones to bind to their target cells.


How does protein hormones reach their target cells?

Usually in blood plasma, which carries them to their target cells. They 'recognize' these cells based on receptors on the cell membranes to which they bind.


Are hormones target molecules or signal molecules?

Hormones affect target cells because target cells have receptors that bind with certain hormones (they're specific). If a cell does not have a receptor then it is not affected by hormones. Target cells (which do have the receptor for a particular hormone) would be affected by the hormone.


How do non steroid hormones control their target cells?

They: Bind to cell membrane receptors Use cAMP as a second messenger and they cause a cascade amplification reaction


Why target cell respond to the hormone while others are uneffected?

Target cells respond to hormones because they have specific receptors for the hormone on their cell membrane or inside the cell. These receptors enable the hormone to bind and initiate a cellular response. Other cells that do not have the specific receptors for that hormone are unaffected because they cannot bind to the hormone or activate the necessary signaling pathways.


A steroid hormone acts on a target cell by?

When receptors bind at the surface of a membrane, second messengers are released. This is how peptide hormones and catecholamines affect target organ cells.


What hormones can enter the target cell and bind to receptors in the nucleus?

steriod hormones - since they are lipophilic and fusses with the membrane to enter teh cell.


Which hormone affect only certain cells?

Because they only activate target cells that have special receptors that only work when that specific hormone attaches to it.


What hormone can enter the target cell and bind to receptors in the nucleus?

steriod hormones - since they are lipophilic and fusses with the membrane to enter teh cell.


How do the signals of the endocrine system get transmitted to their appropriate target cells?

The endocrine system is a system of glands that secrete hormones (made of proteins) into the blood stream. Once in the blood, these hormones bind to other protein called receptors in the membranes of the target cells. This is how signals are transmitted


How do hormones interact with target cell receptors?

The relationship between a hormone and a target cell is that hormones are chemicals released in one part of the body that travel through the bloodstream and affect the activity of cells in the body. Hormones do this by binding to specific chemical receptors on those cells. Target cells have receptors for a particular hormone. Which means is cells do not have receptors or the receptors do not respond to a particular hormone, the hormone has no affect on it.


True or false steroid hormones perform accoding to the second messenger mechanism?

steroid hormones are hydrophobic and bind to transport proteins which bind to receptors within the nucleus. hydrophillic hormones bind to plasma membrane receptors and act through second messenger systems