Lock and Key to the Nth Degree. When any one of 'very many' intercellular 'blood borne' Activating Factors finds & fits-to a Cell Surface Receptor, this causes conformational changes to the 'Transmembrane Signal Proteins' that rapidly become apparent on the cytoplasmic 'side' of the cell membrane as another signal or set of signals, usually directed to the Nucleus.
All hormones have "target cells" upon which they initiate an physiological action. A perfect example is Parathyroid Hormone (PTH). When plasma calcium is low, PTH is stimulated and secreted from the parathyroid gland, and in concert with vitamin D, triggers osteoclasts in bone to initiate bone resporption to raise plasma calcium. In order for this to happen, the hormone has to bind to very specific receptors (usually protein orcarbohydrate macromolecules) on that target cell surface to initiate the action.
Water-soluble hormones. Insulin and epinephrine
the lipid soluble hormone and water soluble hormones, bind to receptor protein to reach the target cell.
Usually in blood plasma, which carries them to their target cells. They 'recognize' these cells based on receptors on the cell membranes to which they bind.
Hormones affect target cells because target cells have receptors that bind with certain hormones (they're specific). If a cell does not have a receptor then it is not affected by hormones. Target cells (which do have the receptor for a particular hormone) would be affected by the hormone.
steriod hormones - since they are lipophilic and fusses with the membrane to enter teh cell.
Because they only activate target cells that have special receptors that only work when that specific hormone attaches to it.
The relationship between a hormone and a target cell is that hormones are chemicals released in one part of the body that travel through the bloodstream and affect the activity of cells in the body. Hormones do this by binding to specific chemical receptors on those cells. Target cells have receptors for a particular hormone. Which means is cells do not have receptors or the receptors do not respond to a particular hormone, the hormone has no affect on it.
Receptors allow hormones to bind to their target cells.
Usually in blood plasma, which carries them to their target cells. They 'recognize' these cells based on receptors on the cell membranes to which they bind.
Hormones affect target cells because target cells have receptors that bind with certain hormones (they're specific). If a cell does not have a receptor then it is not affected by hormones. Target cells (which do have the receptor for a particular hormone) would be affected by the hormone.
They: Bind to cell membrane receptors Use cAMP as a second messenger and they cause a cascade amplification reaction
Target cells respond to hormones because they have specific receptors for the hormone on their cell membrane or inside the cell. These receptors enable the hormone to bind and initiate a cellular response. Other cells that do not have the specific receptors for that hormone are unaffected because they cannot bind to the hormone or activate the necessary signaling pathways.
When receptors bind at the surface of a membrane, second messengers are released. This is how peptide hormones and catecholamines affect target organ cells.
steriod hormones - since they are lipophilic and fusses with the membrane to enter teh cell.
Because they only activate target cells that have special receptors that only work when that specific hormone attaches to it.
steriod hormones - since they are lipophilic and fusses with the membrane to enter teh cell.
The endocrine system is a system of glands that secrete hormones (made of proteins) into the blood stream. Once in the blood, these hormones bind to other protein called receptors in the membranes of the target cells. This is how signals are transmitted
The relationship between a hormone and a target cell is that hormones are chemicals released in one part of the body that travel through the bloodstream and affect the activity of cells in the body. Hormones do this by binding to specific chemical receptors on those cells. Target cells have receptors for a particular hormone. Which means is cells do not have receptors or the receptors do not respond to a particular hormone, the hormone has no affect on it.
steroid hormones are hydrophobic and bind to transport proteins which bind to receptors within the nucleus. hydrophillic hormones bind to plasma membrane receptors and act through second messenger systems